Comparison of bronchial responsiveness to ultrasonically nebulized distilled water (UNDW), methacholine, and ultrasonically nebulized distilled cold water (UDCW) in patients with sulfur mustard gas-induced asthma
نویسندگان
چکیده
منابع مشابه
Comparison of bronchial responsiveness to ultrasonically nebulized distilled water (UNDW), methacholine, and ultrasonically nebulized distilled cold water (UDCW) in patients with sulfur mustard gas-induced asthma
OBJECTIVE To evaluate bronchial challenges using three different stimuli as screening tools for bronchial hyper-responsiveness in sulfur mustard gas-induced asthma. DESIGN Randomized, cross-over clinical study. SETTING University hospital. PATIENTS Eighteen veterans with mustard gas-induced asthma and 18 normal veterans as the control group. INTERVENTION Pulmonary function tests and inh...
متن کاملComparison of ultrasonically nebulized distilled water and cold-air hyperventilation challenges in asthmatic patients.
Cold-air hyperventilation (CAHC) and ultrasonically nebulized distilled water (UNDW) challenges were compared in 11 asthmatic patients who were moderately sensitive to methacholine. The challenges were performed on two separate days within one week of each other. Baseline FEV1 on each test day was greater than 70 percent of predicted. Ten of 11 subjects' FEV1 decreased at least 15 percent, and ...
متن کاملIncrease in bronchial responsiveness to methacholine and late asthmatic response after the inhalation of ultrasonically nebulized distilled water.
We studied ten subjects who had an asthmatic response after the inhalation of ultrasonically nebulized distilled water and did not show any refractory period to repeated challenge with such water. The change in responsiveness to methacholine after inhalation of distilled water and the occurrence of any water-induced late asthmatic response were investigated on separate days. All of the tested s...
متن کاملBronchoconstrictive responses to inhaled ultrasonically nebulized distilled water and airway inflammation in asthma.
Twenty-two asthmatic patients with a range of airway hyperresponsiveness to methacholine underwent a bronchial challenge with ultrasonically nebulized distilled water (UNDW). The presence of positive responses to this stimulus was related to the extent of airway inflammation, as assessed by histochemical and immunohistochemical evaluation of bronchial biopsy specimens. Twelve patients had airfl...
متن کاملAirway hyperresponsiveness to ultrasonically nebulized distilled water in subjects with tetraplegia.
The majority of otherwise healthy subjects with chronic cervical spinal cord injury (SCI) demonstrate airway hyperresponsiveness to aerosolized methacholine or histamine. The present study was performed to determine whether ultrasonically nebulized distilled water (UNDW) induces airway hyperresponsiveness and to further elucidate potential mechanisms in this population. Fifteen subjects with SC...
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ژورنال
عنوان ژورنال: Clinical Toxicology
سال: 2007
ISSN: 1556-3650,1556-9519
DOI: 10.1080/15563650701382730